Effect of lithium on Na+-K+/ATPase activity of brain gray matter in rat

Isbir T, Kaleagasioglu F, Yucelbilgic G

Cerrahpasa J Med 1995;26: 141-143.

BACKGROUND AND DESIGN: In this study we investigated the effect of lithium on Na+-K+/ATPase activity of brain gray matter purified from Wistar rats fed on lithium diet. Plasma and brain gray matter lithium levels were 0.25±0.083 mmol/L and 0.048±0.022 mmol/L, respectively. Na+-K+/ATPase activity in the lithium-treated group (402.08±95.93 nmol Pi/mg Prot/S) was significantly lower than the control group (875.17±59.87 nmol Pi/mg Prot/S) (p<0.001). These findings indicate that Na+-K+/ATPase plays a role in the mechanism of action of lithium. (Return)

The features of twenty cases with Mycoplasma pneumoniae pneumonia

Cokugras H, Soylemez Y, Akcakaya N, Ersoy S, Yilmaz G

Cerrahpasa J Med 1995;26: 144-147.

BACKGROUND AND DESIGN: We have evaluated the features of 20 atypical pneumonia cases caused by Mycoplasma pneumoniae in 1994. The diagnosis of MP was made by high titers of MP IgM. The patients were treated with claritromycin for 14 days and 95% of the cases were cured. One patient died because of bronchiolitis obliterans. Radiological investigation revealed bilateral (45%) involvement of the lower lobes (80%), and pleural fluid (20%). (Return)

Analysis of congenital anomalies of thumb in adults

Durak N, Ozdemir A, Yuksel F, Peker F, Kislaoglu E

Cerrahpasa J Med 1995;26: 148-151.

BACKGROUND AND DESIGN: Thumb is the main finger in hand functions and participates in almost all actions of the hand. Because of closure of bones in adults, more radical surgical procedures are possible to perform. RESULT AND CONCLUSION: 49 cases of 53 patients with congenital thumb anomalies admitted were treated surgically. One case had failure of thumb formation; one macrodactyly; three seperation anomaly, 43 cases had duplication anomalies. Their cosmetic and functional performance were evaluated after a follow-up of at least 6 months. The mildest deformity, duplication, was the most common and the result of treatment was the best. More soft tissues for reconstruction could have been obtained by disarticulative and amputative procedures. It was concluded that deformities of congenital thumb anomalies in adults might benefit better than children by radical surgical procedures. (Return)

The bicoronal incision and subperiosteal approach in the treatment of midfacial fractures

Guzel MZ, Aydin Y, Aygit AC, Celik N, Mindikoglu AN

Cerrahpasa J Med 1995;26: 152-158.

BACKGROUND AND DESIGN: The bicoronal incision and subperiosteal dissection were used in the treatment of 16 patients who sustained complex midfacial fractures. Ten patients had panfacial; 4 had frontoorbital and zygomaticoorbital, and 2 had nasoorbital ethmoidal fractures. Fifteen patients underwent surgical explaration from within hours to as late as one week after the injury. A late operative repair (1 year after the injury) was performed in only one patient who was found to have unoperated nasoethmoidal fracture. RESULTS: The evaluations were made 18 months after surgery with detailed physical examination, standardized photographs, sometimes computed tomography in 8 (CT), and/or three dimensional CT images in three patients. No patient had frontal nerve palsy. Depression in the temporal area due to temporalis muscle atrophy was noted as moderate in one and minimal in 2 patients. No detectable contour deformity of the craniofacial skeleton, enophthalmos, increased scleral show, ectropion, malposition of the lateral canthus, orbital dystopia, or malocclusion were observed. CONCLUSION: The complete exposure of the involved craniofacial skeleton was achived through a combined approach of coronal, subciliary (or midpalpebral), intraoral upper sulcus incision, and subperiostal dissection of the fractured bones in a single surgical session. We have shown that this method was effective in the management of these patients, with optimal anatomical and functional reconstruction. (Return)

Repair of large palatal fistulas with tongue flaps

Guzel MZ, Aydin Y, Aygit AC, Yazar S, Yildirim I

Cerrahpasa J Med 1995;26: 159-164.

BACKGROUND AND DESIGN: The repair of a large palatal fistula is one of the most difficult challenges that a reconstructive surgeon can face. Here we report our results in nine children with large palatal defects ranging from 3x2 cm to 5x3.5 cm. We repaired by using tongue flaps. RESULTS: No comqlication was observed except an early tongue flap dehiscence in one case. CONCLUSION: The results of this series confirm that the anteriorly-based tongue flap is a safe and reliable technique for the closure of large palatal fistulas. (Return)

Granulocytic sarcoma (three cases)

Akun E, Soysal T, Ferhanoglu B, Tuzuner N, Akman N

Cerrahpasa J Med 1995;26: 165-167.

BACKGROUND: Granulocytic sarcoma has been defined as a localized extramedullary tumor composed of immature cells of the granulocytic series. Because it is a rare disease and most of the patients are asyptomatic, the diagnosis is made after postmortem examinations the majority of the cases. OBSERVATION: 17 acute nonlymphoblastic leukemia cases were examined retrospectively. There were three cases, all female with a diagnosis of granulocytic sarcoma based on histopathological examination. In 2 of these patients the localization was breasts (bilateral in one), and gluteal region in the third. (Return)

Endothelin: A humoral factor in vasoconstriction

Karter Y, Yaldiran A, Demir G, Sipahioglu F, Olcay Ozturk E

Cerrahpasa J Med 1995;26: 168-174.

BACKGROUND: Endothelin, one of the active substances synthetised in the endothelial cells, is the most potent vasoconstrictor substance known. In this review the release and effects of endothelin is summarised. (Return)