Prof. Dr. Ekrem Kadri Unat, MD, MPH (1914-1998): Curriculum Vitae and Bibliography
Cerrahpasa J Med 1999;30: 7-28.
Unat had graduated Istanbul University Medical Faculty in 1937; becoming Associate Prof. in 1942 had begun to work in the same faculty; retired in 31.8.1983, then continued his lessons by 24.6.1992 as contracted lecturer. He had carried several studies in USA in between November 1946-October 1949. He had studied on medical mycology in Dermatological Research Laboratory directed by Dr. F. D. Wiedman in Medical School of Pennsylvania University; had attended malariology tropical parasitic diseasess course and also gained his MPH degree in 1948 in Higyene and Public Health School in John Hopkins University; had certificated in medical mycology in Duke University and had studied in Health Laboratory in Maryland; in Health Service Laboratory in New York; in National Institute of Health, Institute of Microbiology Infectional Diseases Laboratory Virus Section in Betshada and had studied in Dr. Emmons' mycology laboratory. He had attended courses on diagnosis in bacteriology, mycology, tuberculosis and parasitical diseasess and had also examined medically important artropodes present in Mediterranean Region, in Atlanta. In his 50 years service life he had teached about 15 thousand students, he consultened to 5 Associate Professors, 46 physicians specialised on microbiolgy and 8 PhD studens in between 1958-1983. He had written 35 books, 1 translated chapter, 10 monographs, 15 meeting books, 10 congress reports and 360 papers; all listed here. Unat had reported either alone or together with his colleagues Shigella sonnei, Dirofilaria conjunctivae, Salmonella eastbourne, Linguatula serrata, Shigella boydii, Cryptococcus neoformans, Toxoplasma gondii, Leptospira canicola, Capillaria hepatica, Pneumocystis carinii, Hymenolepsis diminuta, Sarcophaga in intestins, Lucilia in urinary tract, human Hypodermyasis, Protophormiae terranovae, Gemella haemolyssans as the first in Turkey; had carried detailed researches on microbial antigenes and had reported the first colon cryptococcosis case on the world.(Return)
[Filaria conjunctivae Addario 1885]
Cerrahpasa J Med 1999;30: 29-38.
Es wurde als Ursache eines Tumors der Subcutis der Bauchhaut Filaria conjuctivae Addaria, 1885 nachgewiesen. [Unat EK. Tıp Fakültesi Mecmuası 1944;7(5):3430-3439](Return)
[Uber einen Fall von Infektion mit S. eastbourne]
Cerrahpasa J Med 1999;30: 39-44.
Es wird über eine Infektion mit S. eastbourne berichtet. Der Stamm wurde aus dem Blute eines fiebernden Kindes gezüchtet. Er war indolnegative und zeigte alle typischen kulturell-biochemiscen und serologischen (I, IX, e,h-1,5.) Eigenschaften der S. eastbourne. Er wuchs auch anaerob in einer Ammoniumchlorid-Laktat-Nitrat-Naehrlösung, wie dies für den indol-positiven Eastbourne-Original- stamm charakteristisch ist. [Unat EK. Istanbul Seririyatı 1945;(8):1-7](Return)
An infestation due to larvae of Linguatula serrata
Unat EK, Sahin V
Cerrahpasa J Med 1999;30: 45-52.
The parasites obtained from tonsils, the tonsillar cryptes and the nasal cavities of a patient with the symptomes of irritation of the nasal and pharyngeal mucosae were identified as free (mature) larvae of Linguatula serrata. The source of infestation was the inadequately cooked lymph nodes of a sheep. Infestation lasted for five days. [Unat EK, Sahin V. Tıp Fakültesi Mecmuası 1950;13(3):362-369](Return)
A cryptococcosis case
Soysal SS, Unat EK, Tahsinoglu M
Cerrahpasa J Med 1999;30: 53-75.
(No abstract available) [Soysal SS, Unat EK, Tahsinoglu M. Arch Turk Acad Med 1953;4(16):115-136](Return)
A case of adult toxoplasmosis associated with miliary tuberculosis
Unat EK, Alyanak N, Sahin V
Cerrahpasa J Med 1999;30: 76-98.
We should like to report briefly the first case of toxoplasmosis from Turkey. The patient was a male 37 years of age. He was born in Turkey and he has never been abroad. Last year he suffered from a febrile disease associated with diarrhea. He was admitted to the hospital on 28.XI.1952, the dairrhea successfully treated with sulfaguanidine and paregoric elixir, but an irregular fever persisted. During his hospital stay a histaminoresistent achilia and a pernicious anemia was noted and liver extracts were administered. He left the hospital on 18.XII.1952, but the fever continued to appear at times, antimalaric treatmant were of no use and the patient lost considerable wcight. He noticed swelling in his neck and one week later he waas again obliged to apply to the hospital. In the clinic the patient had an irregular fever ranging between 37,2- and 39 c.. X - ray examination revealed a miliary tuberculosis. One of enlarged cervical lymphatic node was puctured and smear was prepared with the aspirated material and stained by the Pappenheim's panoptic staining procedure. In this slide typical toxoplasmas were found and even their dividing stage were seen. On 3.XI.1953, two days after the definite diagnosis of toxoplasmosis the patient died. Necropsy was performed immediately, but examination of the organs was carried out two days after the necropsy due to week - end vacation. Pathological findings consisted of tubarculous lesions in lungs, spleen, liver, kidneys, thyroid gland and lymphatic nodules. From these organs the tubercle bacilli were isolated as Mycobacterium tuberculosis hominis identified. But apart from these tuberculous manifestations, non tuberculous lesions were found in the stomach, small intetine and some lymphatic glands. In stomach, round shaped ulcers, with diameters 3-18 mm., most of them surrounded with hemorragic halo were noted. Necrotic masses were revealed in the large ulcers. Moreover, in the duodenum and in the first part of the large ulcers. Morcover, in the duodenum and in the first part of the jejunum some foci were observed, which were yellowish white in colour slightly prominent from the surface and surrounded with hyperhemic areas. In the report of Institute of Pathology of the Istanbul University, the histopathological picture of these lesions were described in the following way: In the mucosa of the stomach and small intestine, the areas of destruction, covered with necrotic masses, were observed. the muscularis mucosa is abgent at ulcerations sites. Infiltration of lymphocytes, plasmocytes, histiocytes and polynuclear leucocytes were revealed in the tunica propria at the base of ulcerations of normal mucosa and in submucosa. Among these elements, round or oval the naped and some in elogated from, very small formations (parasites ?) were found. Apart from the gastro-intestinal lesions, in some lymphatic gland (for example in some cervical perigastric and periduodeno-jejunal lymph nodes) pink-brown coloured necrotic foci were noted; they were not associated with caseification, and in histopathological examination they did not make any impression of tuberculosis. They had some elemination they did not make any impression of tuberculosis. They had some elements similar to the toxoplasmas and a histological picture reminding the toxoplasmas and a histological picture reminding the toxoplasmosis. In this case, it possible to postulate that 1. the infection occured by the oral route, 2. there is some relation between achylia and the lesions in the stomach and the small intestine, 3. toxoplasmosis had an activating effect on tuberculosis. [Unat EK, Alyanak N, Sahin V. Presented in Turkish Medical Academy at 18.11.1953](Return)
A case of Capillaria hepatica (Bancroft 1893) Travassos 1915 in the liver of the man
Turhan B, Unat EK, Yenerman M, Sumer C
Cerrahpasa J Med 1999;30: 99-109.
An autopsy case of 60 year old man is reported which presents adults and eggs of Capillaria hepatica in the liver. This case is the third one in the world literature as a Capillaria hepatica in the liver of man. [Turhan B, Unat EK, Yenerman M, Sumer C. Mikrobiologi Derg 1954;7(5-6): 149-159] (Return)
Leptospira canicola infection in Turkey
Unat EK, Gurturk S
Cerrahpasa J Med 1999;30: 110-113.
For the first time in Turkey, from the blood of a dog, showing the symptomes of Sttutgart disease for five days, a strain of Leptospira was isolated by culturing in Korthof's medium and identified as Leptospira canicola by serological methods. [Unat EK, Gurturk S. Mikrobiologi Derg 1954;7(5-6): 179-182](Return)
The first case of infection with Pneumocystis carinii in Turkey
Cerrahpasa J Med 1999;30: 114-121.
By finding the Pneumocystis carinii in the slides, made from the lung of an infant, the occurrence of the infection with this parasite in Turkey was demonstrated. [Unat EK. Turk Mikrobiologi Dergisi 1955;1(1-2): 41-48](Return)
The cases of Hymenolepiasis diminuta in man in Turkey
Unat EK, Bayadal K, Acarer O, Volkan S
Cerrahpasa J Med 1999;30: 122-125.
Hymenolopasis diminuta has been diagnosed in three children living in three different town (Iskenderun, Adana, Tekirdag) of Turkey during a survey made by stoll examinations of nearly 7000 children of primary schools. [Unat EK, Bayadal K, Acarer O, Volkan S. Tıp Fak Mecm 1957;20(1): 153-156](Return)
A case of colon cryptococcosis
Unat EK, Pars B, Kosyak J
Cerrahpasa J Med 1999;30: 126-138.
A case of cryptococcosis localized in the descending colon in a young man, complaining of diarrhea for 8 years, is reported. [Unat EK, Pars B, Kosyak J. Tıp Fak Mecm 1959;22(4): 1318-1330](Return)
Hypodermyiasis in man in Turkey
Unat EK, Kanatli S
Cerrahpasa J Med 1999;30: 139-146.
A case hypodermyiasis caused by the first stage larva of Hypodderma (probably Hypoderma lineatum), localised on the left inguinal region of a 43 year old male farmer has been described. [Unat EK, Kanatlı S. Tıp Fak Mecm 1967;30: 410-417] (Return)
Purulent meningitis due to Gemela hemolyssans
Unat EK, Tanig I, Memis S, Akin A
Cerrahpasa J Med 1999;30: 147-150.
A severe case of purulent meningitis caused by Gemella haemolyssans, initiating 3 days after child delivery is reported. The isolated strain was sensitive to cephalothin. The patient started to improve after addition of cephalothin to bactrim therapy. The patient was discharged in 15 days with complete recovery. (Return)